In genetically predisposed individuals, sensitivity to a class of hormones called androgens, in particular the hormone dihydrotestosterone, or DHT, causes hair follicles to shrink. The scalp begins to sprout hairs that are thinner than normal and fail to grow to normal length.
Eventually the follicles wither away and no hair grows at all. In this scenario, thinning hair eventually progresses to chrome dome stage when the follicles cease to function. But it doesn't have to be that way.

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